Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities.

Adiponectin is an adipokine possessing beneficial effects on obesity-related medical complications.A negative association of adiponectin levels with breast cancer development has been demonstrated.However, the precise role of adiponectin deficiency in mammary carcinogenesis remains elusive.In the present study, MMTV-polyomavirus middle T antigen (M

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Multiset concepts in two-universe approximation spaces

Abstract Rough set theory over two universes is a generalization of rough set model to find accurate approximations for uncertain concepts in information systems in which uncertainty CBD Preroll arises from existence of interrelations between the three basic sets: objects, attributes, and decisions.In this work, multisets are approximated in a cris

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Case Report: Specific ABL-Inhibitor Imatinib Is an Effective Targeted Agent as the First Line Therapy to Treat B-Cell Acute Lymphoblastic Leukemia With a Cryptic NUP214::ABL1 Gene Fusion

Acute lymphoblastic leukemia (ALL) with recurrent genetic lesions, affecting a series of kinase genes, is associated with unfavorable prognosis, however, it could benefit from treatment with tyrosine kinase inhibitors (TKI).NUP214::ABL1 fusion is detected in 6% of T-cell acute lymphoblastic leukemia (T-ALL), and is very rare in B-ALL.We present a c

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